Web3 on hepatoma cell growth, thyroid receptor (TR) 1orTR 1 over-expressing HepG2 cell lines were used. Growth of the HepG2-TR stable cell line was inhibited by over 50% following treatment with T 3. However, transforming growth factor (TGF)- neutralizing antibody, but not the control antibody can reverse the cell growth inhibition effect of T 3. … WebIt is well known that stemness or CSC is a promising mechanism of sorafenib resistance in HCC. 25,26 Our in vitro experiments showed that sorafenib treatment promoted CSC-associated protein expression of the hepatoma cells, while the in vivo experiments showed that PLC/PRF/5 and HepG2 xenograft tumors with higher CSC-associated protein …
Regulation of Angiogenin Expression in Human HepG2 Hepatoma Cells …
Web7 mrt. 2024 · In conclusion, HepG2 cells and primary human hepatocytes respond differently to glucose and fructose treatment in terms of lipid accumulation. The only … WebThe aim of this study was to determine the molecular mechanisms involved in IGFBP-1 upregulation by ethanol.MethodsWe studied IGFBP-1 regulation by ethanol at the protein, mRNA and gene promoter levels in the human hepatocarcinoma cell line, HepG2, which does not express significantly ethanol-metabolizing enzymes.ResultsEthanol … thomas mcdermott nj
HepG2 hepatocytes express IFN-γ, TNF-α, TGF-β, M-CSF, …
WebThe human hepatoma-derived cell line, HepG2, synthesized and secreted functional complement proteins C1r, C1s, C2, C3, C4, C5, factor B, C1 inhibitor, C3b inactivator, a small amount of C6, and trace amounts of C8; but … WebRecent studies report that nuclear factor-erythroid-2-related factor 2 (Nrf2) facilitates tumor progression through metabolic reprogramming in cancer cells. However, the molecular mechanism underly... WebCultures of primary hepatocytes and hepatoma cell line HepG2 are frequently used in in vitro models for human biotransformation studies. In this study, we characterized and … thomas mcdevitt washington times