Paclitaxel mda-mb-231
WebJul 13, 2010 · MDA-MB-231 cells were incubated under normoxic (N) or hypoxic (H) conditions with or without paclitaxel (tax, 50 μM) or epirubicin (epi, 10 μM) for 16 hours. (A) The caspase 3 activity was assayed by measuring free AFC released from the cleavage of the caspase 3 specific substrate Ac-DEVD-AFC. WebMar 31, 2024 · Zou CF, Jia L, Jin H, Yao M, Zhao N, Huan J, Lu Z, Bast RC Jr, Feng Y, Yu Y. Re-expression of ARHI (DIRAS3) induces autophagy in breast cancer cells and enhances the inhibitory effect of paclitaxel. BMC Cancer. …
Paclitaxel mda-mb-231
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WebFeb 2, 2012 · There are 10 doxorubicin and 4 paclitaxel resistant MCF-7 cell lines, 6 doxorubicin and 9 paclitaxel resistant MDA-MB-231 cell lines. The relative resistance values compared to the original cell lines show up to 46 (average: 18.5) fold resistance against doxoxubicin and up to 28 (average: 15.4) fold resistance against paclitaxel. WebOne of the best strategies to circumvent drug resistance is the employment of nanocarriers. For the current study, we have employed a nanoemulsion formulation of paclitaxel …
WebThe pH-responsive activity was evaluated in MDA-MB-231 cell line at pH 6.8 and pH 7.4 by using coumarin-6/SPIO-SSL-H 7 K(R 2) 2 as a tracer. Briefly, MDA-MB-231 cells were … WebNov 1, 2024 · MDA-MB-231/ADR cells were treated with different concentrations of paclitaxel and everolimus. The IC 50 values after 48 h of treatment were measured by …
WebMay 1, 2024 · Combination of two anti-tubulin agents, eribulin and paclitaxel, enhances anti-tumor effects on triple-negative breast cancer through mesenchymal-epithelial transition … WebOct 9, 2024 · The MDA-MB-231 cells were seeded in 96-well plates at a density of 5 × 10 3 cells per well and incubated in medium (100 mL) for 24 hours to complete cell …
WebSep 1, 2024 · Toxicity of paclitaxel towards MCF-7, T47D and MDA-MB-231 cells is associated with drug uptake. • The potentiated toxic effect of paclitaxel in breast cancer …
WebAntitumor activity of the bioreductive prodrug 3-(2-nitrophenyl) propionic acid-paclitaxel nanoparticles (NPPA-PTX NPs) on MDA-MB-231 cells: in vitro and in vivo Xiao-Chuan … pine island florida live webcamWebAug 27, 2024 · 3D cell culture including different cell types, such as immune cells, is a representative platform that mimics the tumor microenvironment. Here we disclose an easy-to-handle 3D co-culture protocol using a scaffold-free technique with the breast cancer cell line MDA-MB-231 and breast cancer patient-derived immune cells from peripheral blood. … pine island florida indian moundsWebTherefore, it is speculated that paclitaxel induces the death of MDA-MB-231 breast cancer cells by first inducing cell expansion, then causing cell rupture, and finally gradually lytic cells . PTX and ProPTX treatment made the cells swell. However, ProPTX-NPs, ProPTX-SS-NPs, and Man-ProPTX-SS-NPs made the cells in the state of rupture and lysis ... pine island florida governmentWebJan 11, 2024 · MDA-MB-231/LM2–4 is a variant of the triple negative human breast cancer cell line MDA-MB-231 (originally obtained from Dr. Jeff Lemontt, Genzyme Corp.) selected in vivo for its aggressive spontaneous metastatic properties after the established orthotopic primary tumor has been resected [ 76 ]. pine island florida hotelWebSep 10, 2024 · MDA-MB-231 cells were treated for 48 h with 0.5 µM palbociclib and 10 nM paclitaxel alone or treated with palbociclib for 24 h and then with paclitaxel for further … pine island florida causewayWebThe MDA-MB-231 cell line derived xenograft (CDX) is an enabling mouse model for assessing preclinical therapies. All models have strengths and weaknesses, most importantly is that single layer in vitro studies do not incorporate vasculature and stroma of the tumor microenvironment. In vivo studies of the MDA-MB-231 CDX model include … pine island florida live camWebOct 31, 2012 · MDA-MB-231 primary tumors were CK18 positive, EGFR positive, Her2 negative ( Figure 1B ), demonstrating that the xenograft tumors retained the MDA-MB-231 cell line expression pattern of key breast cancer markers. At necropsy mice were examined visually for macro-metastases. pine island florida lodging