Tsp 1 antibody

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August undefined, 2024

WebAug 1, 2024 · The LSKL peptide is a competitive antagonist that inhibits TSP-1-TGF-β activation by preventing the interaction of TSP-1's KRFK sequence with the LAP of latent TGF-β (Fig. 1) [23].This antagonist tetrapeptide has been widely used by our lab and others, along with thbs1 (TSP-1) null animals, to establish TSP-1 as a primary regulator of TGF-β … WebThrombospondin-1 (TSP-1) is a secreted homotrimeric protein that regulates a wide range of cellular functions including their interactions with other cells and with the extracellular matrix (ECM). TSP-1 counteracts the angiogenic, hypotensive, and anti-thrombotic effects of nitric oxide (NO). It binds and neutralizes VEGF, blocks VEGF R2 ...

Thrombospondin-1 mediates smooth muscle cell proliferation ... - PubMed

WebLyophilized or Liquid. Concentration. - 100 μg (in 100 μl): 1 mg/ml. Storage. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at … WebFeb 21, 2024 · This is a Validated Antibody Database (VAD) review about human thrombospondin 1, based on 44 published articles (read how Labome selects the articles), using thrombospondin 1 antibody in all methods.It is aimed to help Labome visitors find the most suited thrombospondin 1 antibody. Please note the number of articles fluctuates … simple baked seafood

Mouse Thrombospondin-1 Antibody MAB7859-100: R&D Systems

WebThe Human TSP-1 solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the … WebA purified peptide of the CD47-binding TSP-1 C-terminal domain (E3T3C1) or functional blocking antibodies to TSP-1 (α-TSP-1 C-terminus) or CD47 (α-CD47) were incubated with MVs for 48 hours. Effects of antibody treatment of knockout-derived MVs were not determined (n.d.). WebThrombospondin-1 Antibody (A6.1) Summary. BALB/C mice were injected with reduced and alkylated purified human TSP (fully denatured) from the supernatant of thrombin … raves in myrtle beach

Thrombospondin-1 Antibody (A6.1) - Novus Biologicals

Function-blocking antithrombospondin-1 monoclonal antibodies

WebMay 10, 2010 · Neutralizing TSP-1 antibody (clone A4.1; Thermo Fisher, Fremont, CA, USA) was used at 40 μg/ml as previously described. 5 Controls for the neutralizing activity of this antibody were included in ... Web313 TSP-1 antibodies from 28 antibody suppliers Click each TSP-1 antibody that interests you to view the full TSP-1 antibody datasheet. View only TSP-1 Monoclonal Antibodies or … raves in new mexicoWebApr 7, 2024 · antibody specific for human Thrombospondin-1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any Thrombospondin-1 present is bound by the immobilized antibody. After washing away any unbound substances, an enzyme-linked polyclonal antibody specific for human Thrombospondin-1 is added to … simple baked skinless chicken breasts

"WebMonoclonal Antibody for studying Thrombospondin-1. Cited in 17 publications. Validated for Western Blotting, Immunoprecipitation. Highly specific and rigorously validated in-house, … " - Tsp 1 antibody

Tsp 1 antibody

TSP-1 antibodies - Antibody search engine - CiteAb

WebAnti-TSP-1 Antibody Products. TSP-1 is an alias for the human gene, Protease, serine 55, or, PRSS55. Other names include: Serine protease 55; T-SP1; Serine protease 55 ; CT153; TSP1; protease, serine, 55. The encoded protein is an enzyme with an amino acid length of 352 and a mass of 38.9 kDa. TSP-1 is a member of the Peptidase S1 family. WebHere we characterize a novel TSP-1 interaction with T. cruzi that enhances cellular infection. We show that labeled TSP-1 interacts specifically with the surface of T. cruzi trypomastigotes. We used TSP-1 to pull down interacting parasite surface proteins that were identified by mass spectrometry.

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WebNov 11, 2024 · The recombinant TSP-1 protein promoted proliferation, survival, and migration of CTCL cell lines, and anti-CD47 or anti-TSP-1 neutralizing antibody inhibited …

WebJan 28, 2024 · Macrophage-mediated phagocytosis of liver cancer cells can be enhanced by treatment with an anti-CD47 antibody, a SIRPα blocking antibody, or by blocking the CD47-TSP-1 interaction (64, 65). Attenuation of CD47-SIRPα signaling in cholangiocarcinoma promotes the phagocytotic potential of a variety of macrophage subpopulations and … WebThe cells were labeled with Thrombospondin 1 (A4.1) Mouse Monoclonal Antibody (Product # MA5-13377) at 2 µg/mL in 0.1% BSA and incubated for 3 hours at room temperature and then labeled with ... are presented as mean +- SD. ( c ) Angiogenic activity ( d ) and VEGF levels were evaluated in PrEC as above. ( e ) TSP-1 expression was evaluated by ...

WebAnti-TSP-1 Antibody Products. TSP-1 is an alias for the human gene, Protease, serine 55, or, PRSS55. Other names include: Serine protease 55; T-SP1; Serine protease 55 ; CT153; … WebThrombospondin-1 (TSP-1) is a 150‑180 kDa charter member of the thrombospondin family of extracellular matrix proteins. Human TSP‑1 is synthesized as an 1170 amino acid (aa) precursor that contains an 18 aa signal sequence and 1152 aa mature molecule. The mature molecule has been described as containing three distinct regions that create ...

Web(ab85762) Anti-Thrombospondin 1 antibody Supplier Abcam. Host Rabbit Type Primary Clonality Polyclonal Conjugate Unconjugated Target Thrombospondin-1 (Human) UniProt P07996 - TSP1_HUMAN. Gene ... THBS1, TSP, TSP1, TSP-1, THBS, THBS-1. View additional product information. Experiments from the literature. Loading published images for this …

WebThrombospondin-1 (UniProt P07996; also known as THBS-1, TSP-1) is encoded by the THBS1 (also known as THBS, TSP, TSP1) gene (Gene ID 7057) in human. Thrombospondin-1 (TSP-1) is a member of the TSP family of calcium-binding extracellular matrix proteins. The TSP family consists of the homotrimeric TSP-1 and TSP-2, as well as the … simple baked squashWebFlow cytometry analysis of Thrombospondin in HepG2 cells compared to an isotype control (blue). Cells were harvested, adjusted to a concentration of 1-5x10^6 cells/mL, fixed with … raves in north carolinaWebThe cells were labeled with Thrombospondin 1 (D4.6) Mouse Monoclonal Antibody (Product # MA5-13385) at 2 µg/mL in 0.1% BSA and incubated for 3 hours at room temperature and then ... * P . 0*010 (Student's t test). e Western blotting of thrombospondin (TSP) 1 protein at 6 h after hepatectomy. Expression of TSP-1 was similar in normal saline ... raves in nyc tonightWebLyophilized or Liquid. Concentration. - 100 μg (in 100 μl): 1 mg/ml. Storage. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. raves in new orleansWebThe function of the type II repeats in unclear. TSP‑1 is secreted as a disulfide-linked 450 kDa homotrimer. The cysteines responsible lie just N‑terminal to the first type I TSP repeat. … simple baked sweet potatoWebMouse monoclonal Thrombospondin 1 antibody [A6.1]. ... TSP-1 axis. Diabetes Res Clin Pract 165:108140 (2024). PubMed: 32277954; View all Publications for this product. … simple baked squash recipeWebThese antibodies have been verified by IP-MS, Knockdown and Cell treatment to confirm specificity to Thrombospondin 1. Find the Thrombospondin 1 antibody that fits your needs. Choose from 1 of 22 Thrombospondin 1 antibodies, which have been validated in experiments with 399 publications and 98 images featured in our data gallery. simple baked spaghetti recipe for two